Assessing the comparative effectiveness of Tai Chi versus physical therapy for knee osteoarthritis: design and rationale for a randomized trial. 7.Wang C, Iversen MD, Mcalindon T, et al.Combination of platelet-rich plasma and bone marrow mesenchymal stem cells enhances tendon-bone healing in a rabbit model of anterior cruciate ligament reconstruction. Mesenchymal stem cell therapy in the treatment of osteoarthritis: reparative pathways, safety and efficacy - a review. Stem cells in articular cartilage regeneration. 4.Filardo G, Perdisa F, Roffi A, Marcacci M, Kon E.Therapeutic potential of mesenchymal stem cell based therapy for osteoarthritis. 3.Burke J, Hunter M, Kolhe R, Isales C, Hamrick M, Fulzele S.Risk factors in the development of stem cell therapy.
Concentrated Bone Marrow Aspirate for the Treatment of Chondral Injuries and Osteoarthritis of the Knee: A Systematic Review of Outcomes. 1.Chahla J, Dean CS, Moatshe G, Pascual-garrido C, Serra cruz R, Laprade RF.See Arthritis Treatment Specialists References What are the potential risks and complications?īoth doctors and patients can benefit from having a frank conversation and setting reasonable expectations.How do people with similar joint damage to me respond to treatment?.If using a stem cell injection, will medical imaging be used to ensure accuracy?.What is your experience with this treatment?.People considering stem cell therapy for an arthritic knee or other joint are advised to ask their doctors questions, including: Stem cell therapy can vary depending on the doctor performing it. See Platelet-Rich Plasma Injection Procedure Deciding to Have Stem Cell Therapy for Arthritis Physicians who use PRP and stem cells together think that the PRP can help maximize the healing effects of stem cells. See PRP Injection Preparation and Composition Like stem cell therapy, PRP therapy is sometimes used alone with the hopes of healing an arthritic joint. In the body, platelets secrete substances called growth factors and other proteins that regulate cell division, stimulate tissue regeneration, and promote healing. PRP is derived from a sample of the patient’s blood. See Platelet-Rich Plasma (PRP) Therapy for Arthritis Many physicians combine the use of stem cells with platelet rich plasma, or PRP. For example, how many stem cells are needed for a particular treatment? And how do we determine if a patient’s own stem cells are competent enough to aid in healing? These differences are further complicated by more unknowns. How the stem cells are delivered to the arthritic joint.How stem cells are separated from the rest of the harvested tissue.Where the stem cells are harvested from.So the stem cell therapy in one study is not necessarily the same as the stem cell therapy in another study. Is Stem Cell Therapy for Arthritis Safe and Effective?Ĭritics emphasize that there have been no large-scale, prospective, double-blind research studies-the kind of clinical studies that medical professionals consider the gold standard-to support stem cell therapy for arthritis.įactors that affect stem cell therapy researchĪnother challenge associated with current stem cell research is that there is no standard stem cell therapy for arthritis treatment. 2Īs with most regenerative medicine treatments, research is ongoing, and FDA regulations are relatively new and subject to change. Some research suggests stem cell therapy engaging in these kinds of practices may elevate the risk of tumors. The stem cells are mixed with other chemicals.The stem cells are cultured (taken from the patient and grown in the lab over time).pluripotent stem cells instead of adult stem cells) A different type of stem cell is used (e.g.While most stem cell therapy for arthritis is considered safe, it does carry the same risks as any other medical procedure, such as a small risk of infection. The most common side effects are temporary swelling and pain. Most stem cell therapy using adult stem cells is considered safe because the stem cells are collected from the patient, minimizing the risk of an unwanted reaction. People considering stem cell treatment for arthritis want to know Is it safe? and Is it effective? Stem Cell Therapy Safety
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